Official websiteSafety
Neuralisse Side Effects: What Each Ingredient Can Do and When to Stop
Most people who react to Neuralisse would notice mild stomach upset or loose stools, mainly from magnesium. Rarer risks come from single ingredients: low blood sugar from alpha lipoic acid, liver injury from turmeric, and bleeding changes with warfarin. The label says it is not for anyone under 18, or pregnant or nursing mothers. Stop and call a doctor if warning signs appear.
Written by the Goneuralisse editorial teamUpdated
The short version
What are the side effects of Neuralisse?
The likeliest side effects are mild: an upset stomach, nausea or loose stools. Magnesium supplements can cause diarrhea, nausea and cramping (ODS, Magnesium (HP)), and each capsule holds 80 mg of it.
No study has tested Neuralisse itself. So we looked at each of its six ingredients in NIH, hospital and FDA sources.
Dose matters. The five ingredients after magnesium share at most about 175 mg in the best case, far below the amounts tied to most reported problems. Small doses lower the odds of a reaction. They do not rule out an interaction with your medicine.
Word for word, the label's own warning reads: "Do not exceed recommended dose. Not for use for those under the age of 18 or pregnant or nursing mothers. Consult with a physician prior to use especially if you are taking a medication or have a medical condition."
By ingredient
Which Neuralisse ingredient causes which side effect?
Each ingredient has its own record. The table pairs what the research reports with how much of that ingredient a capsule can hold.
| Ingredient | Per capsule | Side effects reported in research | Who should take extra care |
|---|---|---|---|
| Magnesium glycinate | 80 mg magnesium (printed) | Diarrhea, nausea, stomach cramps at supplement doses (ODS, Magnesium (HP)) | People with weak kidneys, since magnesium can build up (ODS, Magnesium (HP)) |
| Alpha lipoic acid | At most about 175 mg | Low blood sugar, nausea, vomiting, indigestion (MSKCC, Alpha-lipoic acid); vertigo rose with higher doses (SYDNEY 2 trial); rare insulin autoimmune syndrome (Health Canada, ALA hypoglycemia) | Anyone on insulin or diabetes pills |
| Butcher's broom | At most about 87 mg | Diarrhea and skin reactions (MSKCC, Butcher's broom) | People with diabetes are advised to avoid it after a ketoacidosis case (MSKCC, Butcher's broom) |
| L-carnitine | At most about 58 mg | Nausea, cramps, diarrhea and a fishy body odor at about 3 g a day (ODS, Carnitine) | People on thyroid medicine; 2-4 g a day blunted thyroid hormone (Benvenga 2001, carnitine & thyroid) |
| Turmeric | At most about 43 mg | Rare liver injury (MSKCC, Turmeric) (DILIN 2023, turmeric liver injury); gallbladder contraction (LPI, Curcumin) | Blood thinner users, gallbladder disease, pregnancy (NCCIH, Turmeric) |
| Coenzyme Q10 | At most about 35 mg | No serious effects reported; mild insomnia or stomach upset (NCCIH, CoQ10), mostly at 200 mg or more (LPI, CoQ10) | Warfarin and insulin users (NCCIH, CoQ10) |
Ceilings assume the lighter form of magnesium glycinate. The label does not name the form, so real amounts could be lower.
Who should skip it
Who should not take Neuralisse?
The label rules out three groups outright: anyone under 18, pregnant women and nursing mothers. Several more groups should talk to a doctor before the first capsule.
- Under 18, pregnant or nursing: do not use, per the label. Turmeric may also be unsafe in pregnancy (NCCIH, Turmeric).
- Upcoming surgery: tell your surgeon about every supplement, since two ingredients touch bleeding.
The five questions below cover the rest, including kidney, liver and gallbladder disease.
Stop signs
When should you stop Neuralisse and call a doctor?
Stop taking Neuralisse and call your doctor the same day if you notice any sign below. Bring the bottle with you.
Shaky, sweaty, confused
Shakiness, sweating, sudden hunger, a fast heartbeat, dizziness or confusion. If you use a meter, check your sugar. Treat a low the way your care team taught you. Alpha lipoic acid is the ingredient linked to lows (MSKCC, Alpha-lipoic acid).
Dark urine, yellow skin
Dark urine, yellow skin or eyes, pale stools, pain under the right ribs, itching, or unusual tiredness and poor appetite. Turmeric liver injury usually improved after stopping (MSKCC, Turmeric).
Bruises, nosebleeds, blood
Easy bruising, bleeding gums, nosebleeds that will not stop, pink or brown urine, or black stools. This matters most if you take warfarin, aspirin or clopidogrel (LPI, Curcumin).
Swelling of the face, lips or tongue, trouble breathing, fainting, vomiting blood, or a low blood sugar that does not lift after treatment.
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What if nerve symptoms get worse while taking Neuralisse?
Worse symptoms are a reason to see a doctor, not to wait. New or worsening numbness, tingling, burning, weakness, balance trouble or a foot sore that will not heal needs a medical visit, and fast if it came on suddenly.
Neuralisse is not a treatment for neuropathy or any nerve disease. Our nerve health guide explains common causes and tests.
Medicines
Does Neuralisse interact with medicines?
Yes, several ingredients can affect common medicines. The most important pairs involve diabetes medicine, blood thinners, thyroid pills, osteoporosis drugs and certain antibiotics.
Neuralisse is sold as a dietary supplement and is not a drug. Ask your doctor first if you take diabetes medicine, a blood thinner such as warfarin, thyroid medicine, certain antibiotics, osteoporosis drugs or water pills, or have kidney, liver or gallbladder disease: the blend includes alpha lipoic acid, turmeric, CoQ10, L-carnitine, butcher's broom and magnesium. See side effects and interactions.
For a medicine-by-medicine table with spacing times, see Medicines and Neuralisse. Take that list to your pharmacist; it takes them two minutes to check.
If something goes wrong
How do you report a Neuralisse side effect?
Report it in two places: to the FDA for safety, and to the order desk for your money. Your doctor can file a report too.
Stop and get care
Stop the capsules. Call your doctor, or 911 for an emergency. Keep the bottle and its lid.
Write down the details
Note the date you started, what you felt, when it began, and every other medicine or supplement you take. Photograph the bottle base and label.
Tell the FDA through MedWatch
Anyone can report a supplement problem to FDA MedWatch online or by phone at 1-800-FDA-1088. The FDA does not review supplements before they are sold (FDA 101, Dietary supplements), so these reports help it spot problems.
Call the order desk
Phone +1 (302) 200-3480 and give your order ID. The desk can see your order and explain the 60-day money-back guarantee. The website inbox cannot see orders.
The label also prints the distributor, Neuralisse, Aurora, CO 80011, USA. For orders placed through this site, the order desk above is faster.
FAQ
Neuralisse side effects FAQ
Can Neuralisse cause diarrhea?
Yes, it can. Each capsule has 80 mg of magnesium, and magnesium supplements can cause diarrhea, nausea and cramping (ODS, Magnesium (HP)). Butcher's broom has also been linked to diarrhea (MSKCC, Butcher's broom). Taking the capsule with a meal may help. If loose stools last more than a few days, stop and ask your doctor.
Can Neuralisse lower blood sugar?
It might. Alpha lipoic acid, the second ingredient, has been linked to low blood sugar and can add to diabetes medicine (MSKCC, Alpha-lipoic acid) (LPI, Lipoic acid). The capsule holds at most about 175 mg. If you take insulin or diabetes pills, check your sugar more often and talk to your doctor before you start.
Is Neuralisse bad for your liver?
There are no reports about Neuralisse itself, but turmeric extract has been tied to rare liver injury. A U.S. network found 10 cases, including 1 death (DILIN 2023, turmeric liver injury). A capsule holds at most about 43 mg of turmeric. Stop and call a doctor if you notice dark urine or yellow skin or eyes.
Should I stop Neuralisse before surgery?
Ask your surgeon, and tell them you take it. Turmeric may raise bleeding risk, and CoQ10 can change how warfarin works (MSKCC, Turmeric) (MSKCC, CoQ10). Surgeons often ask patients to pause supplements before an operation. Follow their exact instructions on when to stop and restart.
Can I get a refund if Neuralisse gives me side effects?
Yes, within the 60-day money-back guarantee shown on the official order page. Phone +1 (302) 200-3480 and give your order ID. The buyer pays return shipping, so ask the desk about return rules before you mail anything. Report the reaction to your doctor as well.
Who should not take Neuralisse?
The label says no one under 18, and no pregnant or nursing mothers. People with diabetes, those on blood thinners or thyroid medicine, and anyone with kidney, liver or gallbladder disease should ask a doctor first. Bring the bottle so they can see all six ingredients.
Who wrote this
Written and reviewed by
A small team that reads the bottle label line by line, checks every number against public health sources (NIH, NCCIH, MSKCC, FDA, FTC, CDC) and rewrites it in plain English. We do not write for the manufacturer, and we update a page whenever the label, the prices or the evidence changes.
Last updated . See our editorial standards and how we check reviews. This website is run by a U.S. authorized merchant, not by the manufacturer. This site is paid a commission when you buy through its order links.
Keep reading
More about Neuralisse
Medicines and Neuralisse
A medicine-by-medicine interaction table, a daily spacing schedule, and the questions to ask your pharmacist.
Read more
Who it's for
A 5-question fit check, plus who should skip Neuralisse and who needs a doctor's okay first.
Read moreSupplement Facts
Every line of the Neuralisse label typed out, with the blend math the label does not show.
Read moreU.S. authorized Neuralisse merchant
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