Official websiteHow it works
How Neuralisse Works: One Capsule, Six Ingredients, Honest Limits
Neuralisse is one capsule a day that supplies 80 mg of magnesium (19% DV) plus a 575 mg blend of five more nutrients and plant extracts. Magnesium helps regulate muscle and nerve function. The other five are present, but at most about 175 mg combined, well below research doses. It is a daily nutrient, not a treatment for any nerve condition.
Written by the Goneuralisse editorial teamUpdated
The short version
How does Neuralisse work?
Neuralisse works like any daily nutrient capsule: you swallow it, it dissolves, and your gut absorbs what is inside. The one amount printed on the label is 80 mg of magnesium, 19% of the Daily Value (ODS, Magnesium (HP)).
The bottle calls it a "Nerve Support Formula." That is label wording for a dietary supplement. It does not mean the capsule acts like a medicine on damaged nerves. By law, supplements are never FDA approved before sale (FDA, Approval myths).
Each capsule holds a 575 mg proprietary blend of six ingredients. Magnesium glycinate comes first and makes up most of the weight. Alpha lipoic acid, butcher's broom, L-carnitine, turmeric and CoQ10 follow, in that order.
Magnesium has the clearest role: it "is important for regulating muscle and nerve function" (ODS, Magnesium (consumer)). The other five were studied mostly at far larger doses.
The brand graphic
What do the three steps in the How Neuralisse Works graphic mean?
The brand graphic shows three numbered steps. They describe a routine, not a body process. Each step points back to the bottle label.
01 Follow label directions
The label says: "As a dietary supplement, take one (1) capsule daily." No more than that. One capsule covers the whole serving.
02 Product formula
The Supplement Facts tile and the Bottle Label tile point you to what is inside: 80 mg of magnesium and a 575 mg blend. Read the panel before your first dose.
03 Daily routine
The 30 Capsules tile means one bottle lasts 30 days. A routine works best when the capsule is tied to something you already do every day.
A normal day
How does Neuralisse fit into a normal day?
Four small habits. The label only fixes the first one; the rest are sensible add-ons.
- 01
Morning: one capsule
Swallow a single capsule with a glass of water. The label says one a day, so there is no second dose to remember.
- 02
With your first meal
The label sets no time. Food helps fat-soluble CoQ10 get absorbed, so a meal makes a steady anchor.
- 03
Keep a gap from some pills
Magnesium can bind certain antibiotics and bone drugs. Leave at least 2 hours between them.
- 04
Write a weekly note
Jot down sleep, comfort and energy once a week. A short record beats memory when you decide whether to keep going.
Full timing details, missed doses and storage are on the how to use Neuralisse page.
In the body
What does each Neuralisse ingredient do in the body?
The six ingredients fall into three groups: one mineral, three nutrient compounds tied to energy, and two plant extracts.
| Ingredient | Group | What it does in the body | Per capsule |
|---|---|---|---|
| Magnesium glycinate | Mineral | Helps regulate muscle and nerve function, blood sugar and blood pressure (ODS, Magnesium (consumer)) | 80 mg magnesium (printed) |
| Alpha lipoic acid | Nutrient compound | An antioxidant the body makes in small amounts; studied for nerve symptom scores in diabetes (Hsieh 2023, oral ALA meta-analysis) | At most about 175 mg |
| Butcher's broom | Plant extract | Studied for heavy, tired legs from weak leg veins, not for nerves (MSKCC, Butcher's broom) | At most about 87 mg |
| L-carnitine | Nutrient compound | Carries fats into cells so they can be burned for energy (ODS, Carnitine) | At most about 58 mg |
| Turmeric | Plant extract | Curcuminoids studied for inflammation; evidence is not enough for any health use (NCCIH, Turmeric) | At most about 43 mg |
| Coenzyme Q10 | Nutrient compound | Part of the energy machinery inside cells; fat-soluble (LPI, CoQ10) | At most about 35 mg |
"At most about" figures are best-case ceilings worked out from label order. The real amounts may be lower.
The blend math
How much of each ingredient fits in one 575 mg capsule?
Most of the capsule is magnesium glycinate. To deliver 80 mg of magnesium, the blend needs about 400 to 567 mg of it, which leaves at most about 175 mg for the other five (FDA, Labeling guide ch. IV).
- 575 mg
The whole proprietary blend in one capsule. The label lists six ingredients, heaviest first (FDA, Labeling guide ch. IV).
- 400-567 mg
The 80 mg of magnesium on the label has to come from magnesium glycinate. Pure magnesium bisglycinate is about 14% magnesium (24.3 / 172.4), so it takes about 567 mg. Buffered forms near 20% magnesium take about 400 mg.
- 8-175 mg
What is left for the other five ingredients together. Because they are listed by weight, the second one can be at most half of that, the third a third, and so on.
The most each ingredient can weigh per capsule
- Alpha lipoic acid≤ 175 mg
- Butcher's broom≤ 87 mg
- L-carnitine≤ 58 mg
- Turmeric≤ 43 mg
- Coenzyme Q10≤ 35 mg
Best case: the lighter, 20%-magnesium form of glycinate. If the glycinate is pure bisglycinate, all five share about 8 mg. The label does not say which form is used.
Give Neuralisse a 60-day trial1 capsule a day · from $49 a bottle · free U.S. shipping on 3 or 6 bottles
Order nowAfter you swallow it
What happens after you swallow a Neuralisse capsule?
The vegetable capsule shell (hypromellose) dissolves in your stomach. Each ingredient is then absorbed in its own way, and food changes how some of them get in.
Magnesium
Absorbed in the small intestine. Healthy kidneys clear the extra, which is why weak kidneys need a doctor's input (ODS, Magnesium (HP)).
CoQ10
Under 5% of an oral dose reaches the blood. A meal with some fat helps it absorb (LPI, CoQ10).
Alpha lipoic acid
Taking it with food lowered peak blood levels by about 30% in studies (LPI, Lipoic acid).
Turmeric
Curcumin is poorly absorbed and quickly cleared from the body (LPI, Curcumin). Neuralisse does not list piperine, the pepper extract some brands add.
Honest limits
What can Neuralisse not do?
Neuralisse cannot treat, reverse or repair nerve damage, and it is not a neuropathy treatment. No published trial has tested Neuralisse itself.
- It cannot replace blood sugar control, which is the main way to keep diabetic nerve damage from getting worse (NIDDK, Diabetic peripheral neuropathy).
- It cannot fix low vitamin B12, a common and treatable cause of numb, tingling feet (ODS, Vitamin B12). It contains no B12.
- It cannot match the 600 mg of alpha lipoic acid used in most nerve trials (SYDNEY 2 trial).
- It cannot stand in for a yearly foot exam and daily foot checks (CDC, Diabetes and your feet).
New or worsening numbness, tingling, burning, weakness, a foot sore that will not heal, or trouble with balance needs a medical checkup. Go fast if it starts suddenly.
By the numbers
What are the key Neuralisse numbers?
The bigger picture
Where does Neuralisse fit in a nerve health plan?
Neuralisse fits best as a small, steady nutrient habit next to the things that matter most. Those are a checkup, blood sugar and blood pressure near goal, and daily foot care (NIDDK, Diabetic peripheral neuropathy).
If you take diabetes medicine, talk to your doctor first. Alpha lipoic acid can lower blood sugar and add to those drugs (LPI, Lipoic acid). The full list is on the medicines and Neuralisse page.
Read the full label on the Supplement Facts page, or see what the label claims and what the evidence supports. If you decide to try it, the official order page shows a 60-day money-back guarantee.
FAQ
How Neuralisse works: common questions
How does Neuralisse work in the body?
Neuralisse supplies 80 mg of magnesium (19% DV) a day, a mineral that helps regulate muscle and nerve function. It also adds small amounts of alpha lipoic acid, butcher's broom, L-carnitine, turmeric and CoQ10. It is a daily nutrient habit, not a drug, and no trial has tested the product itself.
What is the main ingredient in Neuralisse?
Magnesium glycinate is the main ingredient. It comes first on the label and makes up about 400 to 567 mg of the 575 mg blend, enough to deliver the 80 mg of magnesium printed on the bottle. The other five ingredients share what is left, at most about 175 mg.
Can Neuralisse fix nerve damage?
No. Neuralisse is a dietary supplement and is not intended to diagnose, treat, cure or prevent any disease. No study shows it repairs nerves. If you have numbness, tingling or burning, see a doctor to find the cause, such as diabetes or low vitamin B12.
Why is Neuralisse taken only once a day?
The label says to take one capsule daily and not to exceed that dose. One capsule holds the full 30-serving plan: 30 capsules last 30 days. Taking more would raise your magnesium intake and is not what the label directs.
Should I take Neuralisse with food?
The label gives no time of day, but a meal is a sensible choice. CoQ10 is fat-soluble and absorbs better with food. Food lowers alpha lipoic acid peaks by about 30%, a small tradeoff at these amounts against a habit you will keep.
How is Neuralisse different from a neuropathy medicine?
Neuropathy medicines are drugs tested and approved by the FDA for a disease. Neuralisse is a dietary supplement, so the FDA does not approve it, and it makes no disease claim. Its label calls it a Nerve Support Formula with Nerve Health, Comfort Support and Nutritional Support icons.
Who wrote this
Written and reviewed by
A small team that reads the bottle label line by line, checks every number against public health sources (NIH, NCCIH, MSKCC, FDA, FTC, CDC) and rewrites it in plain English. We do not write for the manufacturer, and we update a page whenever the label, the prices or the evidence changes.
Last updated . See our editorial standards and how we check reviews. This website is run by a U.S. authorized merchant, not by the manufacturer. This site is paid a commission when you buy through its order links.
Keep reading
More about Neuralisse
How to use
One capsule a day, the best time to take it, medicine spacing, missed doses and storage.
Read more
Supplement Facts
Every line of the Neuralisse label typed out, with the blend math the label does not show.
Read more
Ingredients
All six Neuralisse ingredients in label order, with the most each capsule can hold and what research used.
Read moreU.S. authorized Neuralisse merchant
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