Ingredient 6 of 6
Coenzyme Q10 in Neuralisse: The Smallest Share of the Blend
Coenzyme Q10, listed as ubiquinone, comes last in the Neuralisse blend, so a capsule holds at most about 35 mg. Studies used 100 to 400 mg a day. It is absorbed better with food, statins lower the body's own CoQ10, and it may interact with warfarin and insulin. Only one trial has looked at painful diabetic nerve problems.
Written by the Goneuralisse editorial teamUpdated
The basics
What is coenzyme Q10 (ubiquinone)?
Coenzyme Q10, or CoQ10, is a fat-soluble compound found in nearly every cell. It helps mitochondria turn food into usable energy. Your body makes it, and small amounts come from meat and fish.
It exists in two main forms. Ubiquinone is the oxidized form, and ubiquinol is the reduced form. The Neuralisse label specifies "Coenzyme Q10 (as Ubiquinone)," the form most supplements use. It is the sixth and last name in the 575 mg blend.
| Label name | Coenzyme Q10 (as Ubiquinone) |
|---|---|
| What it is | Ubiquinone, vitamin-like compound |
| Position in the blend | 6 of 6 (labels list blend ingredients from most to least by weight) |
| Amount per capsule | Not disclosed. At most about 35 mg by label order (part of the 575 mg blend). |
| Amount used in research | 100-400 mg a day in trials |
| Strength of evidence | Limited (one nerve trial) |
| Main use studied | Part of the cell's energy machinery |
| Main caution | May weaken warfarin; may interact with insulin; mild stomach upset. |
Per capsule
How much CoQ10 is in Neuralisse?
At most about 35 mg per capsule in the best case. Studies of CoQ10 commonly used 100 to 400 mg a day (LPI, CoQ10).
No amount is printed, so the figure comes from label order (FDA, Labeling guide ch. IV). Once magnesium glycinate takes its share, no more than about 175 mg is left for five ingredients. CoQ10 is the lightest of them, so it can weigh no more than a fifth of that space. If the glycinate is the purer form, the real figure could be just a few milligrams.
| Item | CoQ10 per day | What it tells you |
|---|---|---|
| Neuralisse, best case | About 35 mg | Ceiling from blend order; likely lower |
| Low end of studies | 100 mg | Neuralisse is about a third of this at most |
| High end of studies | 400 mg | Neuralisse is under a tenth of this |
| Stomach effects start | Around 200 mg and up (LPI, CoQ10) | Neuralisse sits well below that level |
Timing
Should you take CoQ10 with food?
Yes, a meal helps. CoQ10 dissolves in fat, and under 5% of an oral dose reaches the bloodstream, so taking it with food is the usual advice (LPI, CoQ10).
The Neuralisse label sets no time of day. Since CoQ10 favors a meal, one capsule with breakfast or lunch is a sensible default. A meal with some fat, such as eggs, yogurt or nuts, fits well.
The capsule also holds alpha lipoic acid, which absorbs somewhat less with food. With such small amounts, consistency matters more than perfect timing. Our how to use Neuralisse guide sets out a simple daily routine.

Statins
Do statins lower CoQ10?
Yes. Statins such as lovastatin, atorvastatin and simvastatin can lower the body's CoQ10 levels (MSKCC, CoQ10). They block a pathway that the body uses to make both cholesterol and CoQ10.
NCCIH says CoQ10 does not appear to reduce statin-related muscle pain (NCCIH, CoQ10). A review of studies at 100 to 400 mg a day reached the same result (LPI, CoQ10).
Keep taking your statin as prescribed. If muscle aches bother you, talk to your doctor rather than counting on the small CoQ10 amount in Neuralisse.
Medicines
Does CoQ10 interact with warfarin or insulin?
It may interact with both. NCCIH lists warfarin and insulin as possible interactions (NCCIH, CoQ10). In a few reported cases, CoQ10 reduced warfarin's effect, so INR checks are advised (LPI, CoQ10).
Talk to your doctor before you start Neuralisse. Ask whether to check your INR or blood sugar more often for the first few weeks, and do not change your medicine dose yourself.
This blend stacks a few related cautions. Turmeric may add bleeding risk with blood thinners, while alpha lipoic acid may lower blood sugar. Our medicines and Neuralisse page brings them together in one place.

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Does CoQ10 help nerve pain from diabetes?
The evidence is thin. Memorial Sloan Kettering says support for CoQ10 in painful diabetic nerve problems rests on a single placebo-controlled trial (MSKCC, CoQ10).
One trial is a starting point, not an answer. Results need to be repeated in more people, by other teams, before anyone can rely on them.
- One placebo-controlled trial in painful diabetic nerve problems
- Typical study doses: 100 to 400 mg a day
- No trial of CoQ10 at 35 mg for nerve symptoms that we found
- No published trial of Neuralisse itself
Our view
Is the CoQ10 in Neuralisse a plus or a minus?
It is a well-tolerated nutrient in an amount too small to judge. NCCIH reports no serious side effects, with only mild sleep trouble or stomach upset possible (NCCIH, CoQ10).
Good points
- Named form (ubiquinone) on the label
- Few side effects reported
- Low amount stays below the 200 mg level linked to stomach effects
Weak points
- Last in the blend, at most about 35 mg
- Well below the 100 to 400 mg studied
- Only one nerve-related trial exists
- Possible warfarin and insulin interactions
Bottom line
What should you know before taking CoQ10 in Neuralisse?
Take the capsule with a meal, tell your doctor if you use warfarin, insulin or a statin, and keep expectations modest. CoQ10 is the smallest piece of a blend that is mostly magnesium glycinate.
Neuralisse is a supplement, not a treatment for diabetic nerve pain or any disease. If numbness, tingling or weakness is new, getting worse or came on suddenly, or a foot sore will not heal, see a doctor promptly.
FAQ
CoQ10 in Neuralisse: common questions
How much CoQ10 is in Neuralisse?
The label does not say. CoQ10 is last in a 575 mg blend that must also supply 80 mg of magnesium from magnesium glycinate, so the best case is about 35 mg per capsule. Most CoQ10 studies used 100 to 400 mg a day.
How do ubiquinone and ubiquinol differ?
Ubiquinone is the oxidized form of CoQ10 and ubiquinol is the reduced form. The body can use both. Neuralisse lists Coenzyme Q10 as ubiquinone, the form found in most supplements, but it does not print an amount.
Should I take CoQ10 in the morning or at night?
The time matters less than taking it with food, because CoQ10 is fat-soluble and poorly absorbed on its own. The Neuralisse label sets no time, so one capsule with breakfast or lunch is an easy routine. Mild trouble sleeping has been reported.
Should I take CoQ10 if I am on a statin?
Statins can lower your body's CoQ10, but NCCIH says CoQ10 does not appear to ease statin muscle pain. Keep taking your statin as prescribed, and talk to your doctor about muscle aches instead of relying on a supplement.
Can CoQ10 interfere with warfarin?
It may. CoQ10 reduced warfarin's effect in a few reported cases, so frequent INR checks are advised. If you take warfarin, ask your doctor before starting Neuralisse, which also contains turmeric, another ingredient with a blood thinner caution.
Does CoQ10 lower blood sugar?
NCCIH lists insulin as a possible CoQ10 interaction. The blend also includes alpha lipoic acid, a known blood sugar lowerer. If you use insulin or other diabetes medicine, ask your doctor before starting and check your glucose as advised.
Is CoQ10 good for neuropathy?
Evidence is limited to a single placebo-controlled trial in painful diabetic nerve problems. That is not enough to rely on, and Neuralisse holds at most about 35 mg. Neuralisse is not a treatment for neuropathy, and nerve symptoms deserve a doctor's exam.
Who wrote this
Written and reviewed by
A small team that reads the bottle label line by line, checks every number against public health sources (NIH, NCCIH, MSKCC, FDA, FTC, CDC) and rewrites it in plain English. We do not write for the manufacturer, and we update a page whenever the label, the prices or the evidence changes.
Last updated . See our editorial standards and how we check reviews. This website is run by a U.S. authorized merchant, not by the manufacturer. This site is paid a commission when you buy through its order links.
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Medicines and Neuralisse
A medicine-by-medicine interaction table, a daily spacing schedule, and the questions to ask your pharmacist.
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